Acids Magnets

Map of amino acids

Somewhere, something incredible is waiting to be known.

chemical structures of amino acids

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chemical structures of amino acids

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Nirenberg's genetic codon table. This chart from late 1965 lists the initial research on correspondence between genetic units called codons (down left) and amino acids (across top). This research was carried out by US biochemist Marshall Warren Nirenberg (1927-2010) and others at the US National Institutes of Health. By 1966, Nirenberg announced that he had deciphered the 64 RNA codons for all 20 amino acids. The red boxes show potential matches. For the final results of the research, see image C025/9215. Nirenberg shared the 1968 Nobel Prize in Physiology or Medicine for this fundamental work on genetics and amino acids.

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The genetic code describes the information contained in DNA, which is transcribed into RNA messages (or mRNA), then translated when codons (consisting of groups of three nucleotides) are "decoded" into amino acids, the building blocks of proteins. Each cell has “machinery” that can read the codons in mRNA, which direct the synthesis of proteins by specifying the order of amino acids used to build each protein. The genetic code has 64 different codons. This code specifies how the different combinations of nucleotides that make up these codons are “decoded” to tell the machinery each amino acid to add as a protein is built. All but three of the codons "code" for amino acids, and the remaining three are called stop codons. The stop codons a...

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The perfect pair